© 1999 by Oxford University Press
Journal of the National Cancer Institute, Vol. 91, No. 6, 501,
March 17, 1999
© 1999 Oxford University Press
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Five Cervical Studies Show Cisplatin-Based Chemoradiation Reduces Deaths
Gynecologic Oncology Group (GOG) 85: The 3-year survival rate is 67%
for women receiving radiation with cisplatin and 5-fluorouracil compared to 57% for those
receiving radiation therapy and hydroxyurea. (Whitney, C.W., et al., Journal of Clinical
Oncology, in press)
Radiation Therapy Oncology Group (RTOG) 9001: The 3-year survival rate
for women receiving radiation with cisplatin and 5-FU is 75% compared to 63% for women
receiving radiation alone. (Morris, M., et al., New England Journal of Medicine, in
press; available on the journal's Web site: www.nejm.org.)
Gynecologic Oncology Group (GOG) 120: In two groups receiving radiation
and chemotherapy including cisplatin, the 3-year survival rate is 65% compared to 47% for
women receiving radiation and hydroxyurea. (Rose, P.G., et al., New England Journal of
Medicine, in press; available on the journal's Web site: www.nejm.org.)
Southwest Oncology Group (SWOG) 8797: The 3-year survival rate for
women receiving radiation and cisplatin and 5-FU is 87% compared to 77% for women receiving
radiation alone. (Peters, W., et al., to be presented at the annual meeting of the Society of
Gynecologic Oncology, March 22, 1999; available on the SGO Web site: www.sgo.org.)
Gynecologic Oncology Group (GOG) 123: With half of the patients followed
for 35.7 months or more, 83% of those who received concurrent cisplatin and radiation therapy
are alive, compared to 74% of those treated with radiation therapy alone. (Keys, H.M., et al., New England Journal of Medicine, in press; available on the journal's Web site: www.nejm.org.)
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