Skip Navigation


Journal of the National Cancer Institute Advance Access originally published online on October 30, 2009
JNCI Journal of the National Cancer Institute 2009 101(22):1536-1537; doi:10.1093/jnci/djp422
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
101/22/1536    most recent
djp422v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Brower, V.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Brower, V.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© Oxford University Press 2009.

NEWS

Search for New Treatments Intensifies for Triple-Negative Breast Cancer

Vicki Brower

The first 10% of the full text of this article appears below.

Many physicians consider triple-negative breast cancer (TNBC) the most difficult type to treat, and some patients think it is a death sentence. This subtype of breast cancer is extremely aggressive, has limited treatment options, and carries a high risk of recurrence and death. Unlike breast cancers that express hormone receptors for estrogen and/or progesterone and overexpress the HER-2/neu protein, TNBC is negative for all three proteins, so it cannot be treated with drugs specifically targeted at them. Although TNBC accounts for only 15% of breast cancer, it causes a disproportionate number of deaths, particularly among young, black, and Hispanic women, and those with BRCA1 and BRCA2 mutations.

But a spate of recent studies has some experts feeling more optimistic. "Triple negative breast . . . [Full Text of this Article]

Vaccines

More Targets


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?