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Journal of the National Cancer Institute Advance Access published online on October 26, 2009
JNCI Journal of the National Cancer Institute, doi:10.1093/jnci/djp371
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© The Author 2009. Published by Oxford University Press.

CORRESPONDENCE

Re: Anti-Angiogenic Therapy Using Thalidomide Combined With Chemotherapy in Small Cell Lung Cancer: A Randomized, Double-Blind, Placebo-Controlled Trial

Khaled M. Musallam

Ali T. Taher

Affiliation of authors: Hematology and Oncology Division, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon (KMM, ATT)

Correspondence to: Ali T. Taher, MD, Hematology and Oncology Division, Department of Internal Medicine, American University of Beirut Medical Center, PO Box 11-0236, Riad El-Solh, Beirut 1107 2020, Lebanon (e-mail: ataher@aub.edu.lb).

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Lee et al. (1) recently reported the results of a randomized, double-blind, placebo-controlled trial in small cell lung cancer combining the anti-angiogenic drug thalidomide with carboplatin and etoposide chemotherapy. The addition of thalidomide to the chemotherapy regimen was associated with decreased survival of patients with extensive disease and increased risk of thromboembolic events (TEE). . . . [Full Text of this Article]


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