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© Oxford University Press 2007.
IN THIS ISSUE
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Long-Term Preventive Effect of Tamoxifen on Breast Cancer Risk
Tamoxifen is not only an effective treatment for estrogen receptor (ER)-positive breast cancer, but it also reduces the risk of breast cancer in high-risk women. Reports from randomized trials show that both of these effects appear to persist beyond the active treatment period. However, tamoxifen also causes a range of side effects, including thromboembolic events and endometrial cancer. In this issue, Cuzick et al. (p. 272) report the results of an extended follow-up of the IBIS-I trial, which randomly assigned more than 7,000 high-risk women to take daily tamoxifen or
Test of New Selection Protocol for Lynch Syndrome Screening
Risk of Secondary Sarcoma In Childhood Cancer Survivors
KISS1 Secretion and Processing and Metastasis Suppression
Bisphosphonate Dosing Regimens in a Metastasis Model
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J Natl Cancer Inst 2007 99: 258-260.
J Natl Cancer Inst 2007 99: 261-263.
J Natl Cancer Inst 2007 99: 272-282.
J Natl Cancer Inst 2007 99: 283-290.
J Natl Cancer Inst 2007 99: 291-299.
J Natl Cancer Inst 2007 99: 300-308.
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J Natl Cancer Inst 2007 99: 322-330.