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JNCI Journal of the National Cancer Institute 2007 99(3):190-195; doi:10.1093/jnci/djk074
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© Oxford University Press 2007.

NEWS

Lung Cancer Screening Debate Continues Despite International CT Study Results

Renee Twombly

The first 150 words of the full text of this article appear below.

Earlier this year, a lung cancer screening study received worldwide press when it found that computed tomography (CT) screening of patients at risk for lung cancer can lead to early detection. But the disputed report has not reduced the distance between two sparring groups of researchers.

The critical issue is whether CT screening can reduce lung cancer deaths: the ultimate test of any effective cancer screening. Can a screening clinical trial with no control arm can prove a reduction in mortality? This study, the International Early Lung Cancer Action Program (I-ELCAP), had no control arm.

Investigators leading the I-ELCAP study argue that, despite their nonrandomized study design, there is no longer doubt that CT screening saves lives. In their October 26 New England Journal of Medicine report, the researchers estimated 10-year survival at 92% among patients whose stage 1 cancers were detected by CT and removed by surgery.

"We've shown . . . [Full Text of this Article]

Most Sensitive Screening Tool

But Does It Save Lives?

Randomize Treatment?


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J Natl Cancer Inst 2007 99: 191. [Extract] [Full Text] [PDF]



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