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JNCI Journal of the National Cancer Institute 2007 99(2):176-177; doi:10.1093/jnci/djk023
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© The Author 2007. Published by Oxford University Press.

CORRESPONDENCE

Response: Re: Survival With Aromatase Inhibitors and Inactivators Versus Standard Hormonal Therapy in Advanced Breast Cancer: Meta-analysis

John P. A. Ioannidis, Davide Mauri, Nikolaos P. Polyzos, Nicholas Pavlidis

Affiliations of authors: Department of Hygiene and Epidemiology (JPAI, NPP) and Department of Medical Oncology (DM, NP), University of Ioannina School of Medicine, Ioannina, Greece

Correspondence to: John P. A. Ioannidis, MD, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, University Campus, Ioannina 45110, Greece (e-mail: jioannid@cc.uoi.gr).

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Bria et al. assert that phase II trials should not be included in analyses of survival simply because these trials do not have survival as the primary objective but only as a secondary objective. However, this point goes against the fundamental concept and practice that a meta-analysis should be systematically inclusive. An inclusive . . . [Full Text of this Article]


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Related Correspondence

Re: Survival With Aromatase Inhibitors and Inactivators Versus Standard Hormonal Therapy in Advanced Breast Cancer: Meta-analysis
Emilio Bria, Paolo Carlini, Francesco Cognetti, Edmondo Terzoli, and Diana Giannarelli
J Natl Cancer Inst 2007 99: 176. [Extract] [Full Text] [PDF]