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JNCI Journal of the National Cancer Institute 2007 99(2):105-107; doi:10.1093/jnci/djk046
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© Oxford University Press 2007.

NEWS

RESOURCEFUL RODENTS

Personal Mouse Colonies Give Hope for Pancreatic Cancer Patients

Ken Garber

The first 10% of the full text of this article appears below.

Despite much talk about individualized therapy, nearly all cancer patients are still treated based on clinical trials of patients with general tumors, not the particulars of their specific tumor.

"There are many drugs for which we don't have a clue on how to select patients," said Carlos Arteaga, M.D., of Vanderbilt University in Nashville, at the American Association for Cancer Research International Conference on Molecular Diagnostics last September.

The search for predictive tumor biomarkers has been hampered by the shortage of available tissue banks and delayed by the need to validate such markers in prospective clinical trials. But researchers at the Johns Hopkins Kimmel Cancer Center in Baltimore are trying one creative new approach to speed things up. There, a group led by Manuel Hidalgo, M.D., Ph.D., is creating large . . . [Full Text of this Article]

Mining for Markers

Personal Problems


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