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Journal of the National Cancer Institute Advance Access originally published online on September 25, 2007
JNCI Journal of the National Cancer Institute 2007 99(19):1490; doi:10.1093/jnci/djm137
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Published by Oxford University Press 2007.

CORRESPONDENCE

Re: MLH1 –93G>A Promoter Polymorphism and the Risk of Microsatellite-Unstable Colorectal Cancer

Richard A. Hubner, Richard S. Houlston

Affiliations of authors: Section of Cancer Genetics, Institute of Cancer Research, Sutton, UK

Correspondence to: Richard A. Hubner, MA, BM, BCh, Institute of Cancer Research, Section of Cancer Genetics, 15 Cotswold Rd, Sutton, SM2 5NG, UK. (e-mail: richard.hubner@icr.ac.uk).

The first 10% of the full text of this article appears below.

Raptis et al. (1) propose an association between the MLH1 –93G>A polymorphism and colorectal cancers with high microsatellite instability (MSI-H) status and suggest that this variant is a low-penetrance allele for colorectal cancer susceptibility. Although it is plausible . . . [Full Text of this Article]


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Related Article in JNCI

MLH1 –93G>A Promoter Polymorphism and the Risk of Microsatellite-Unstable Colorectal Cancer
Stavroula Raptis, Miralem Mrkonjic, Roger C. Green, Vaijayanti V. Pethe, Neerav Monga, Yuen Man Chan, Darshana Daftary, Elizabeth Dicks, Banfield H. Younghusband, Patrick S. Parfrey, Steven S. Gallinger, John R. McLaughlin, Julia A. Knight, and Bharati Bapat
J Natl Cancer Inst 2007 99: 463-474. [Abstract] [Full Text] [PDF]

Response to this Correspondence

Response: Re: MLH1 –93G>A Promoter Polymorphism and the Risk of Microsatellite-Unstable Colorectal Cancer
Stavroula Raptis, Miralem Mrkonjic, Roger C. Green, Darshana Daftary, Vaijayanti Pethe, Elizabeth Dicks, Banfield H. Younghusband, Patrick S. Parfrey, Steven S. Gallinger, John R. McLaughlin, Julia A. Knight, and Bharati Bapat
J Natl Cancer Inst 2007 99: 1490-1491. [Extract] [Full Text] [PDF]