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JNCI Journal of the National Cancer Institute 2007 99(16):1213; doi:10.1093/jnci/djm121
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© Oxford University Press 2007.

IN THIS ISSUE

The first 10% of the full text of this article appears below.

Choline, One-Carbon Metabolism, and Colorectal Adenoma

One-carbon metabolism is a network of biochemical pathways that plays a central role in the synthesis, repair, and modification of DNA and may therefore have a role in carcinogenesis. Epidemiologic studies have suggested that decreased intake of folate and methionine and increased intake of alcohol—all dietary factors involved in one-carbon metabolism—are associated with an increased risk of colorectal adenoma, a precursor of colorectal cancer. Choline and betaine also are important factors in one-carbon metabolism, but their effect on colorectal adenoma risk was not known. Cho et al. (p. 1224) assessed . . . [Full Text of this Article]

Arterial Thromboembolic Events and Treatment with Bevacizumab

Liver Cancer Chemoprevention and Vitamin/Mineral Combinations

Mortality after Second Cancers in Testicular Cancer Survivors

Lung Cancer Classification by Profiling of Adjacent Tissue

Epigenetic Loss of Imprinting of the IGF2 gene in Wilms Tumors


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