Journal of the National Cancer Institute Advance Access originally published online on July 10, 2007
JNCI Journal of the National Cancer Institute 2007 99(14):1070-1071; doi:10.1093/jnci/djm072
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© Oxford University Press 2007.
NEWS |
Chemotherapy-Induced Pain Puzzles Scientists
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Some patients describe the pain like walking on shards of glass or hot coals. They complain of a tingling numbness on the palms of their hands and the soles of their feet. Cancer patients rank it near the most intense pain imaginable, 8 or 9 on a 10-point scale. But researchers still don't understand what causes it or why some people treated with chemotherapy suffer for months or years—while others never experience it at all.
Chemotherapy-induced neuropathy is a loss of sensation in the fingers and toes—a stocking-and-glove distribution—that disrupts normal life for its victims. Patients report having difficulty with simple
Ignoring the Problem
Treating the Pain