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JNCI Journal of the National Cancer Institute 2006 98(8):508-510; doi:10.1093/jnci/djj172
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© Oxford University Press 2006.

NEWS

Negative Women's Health Initiative Findings Stir Consternation, Debate Among Researchers

Renee Twombly

The first 150 words of the full text of this article appear below.

New results from the largest, most comprehensive, and most expensive study of women's health ever conducted in the United States have run counter to some widely held beliefs.

The Women's Health Initiative (WHI), designed to address the most common causes of death, disability, and poor quality of life in postmenopausal women, has concluded that none of the interventions for cardiovascular disease, cancer, and osteoporosis studied in this 15-year program offers a major benefit.

WHI researchers learned in 2002 that combined estrogen and progestin hormone replacement therapy (HRT) in older women hurt more than it helped, and papers published in February 2006 concluded that a low-fat diet did not reduce heart disease or colon cancer rates. Although the diet may lower breast cancer rates in some women, the overall difference was not statistically significant. A final study, reported later that month, found that calcium and vitamin D supplements also offered no . . . [Full Text of this Article]

Ambitious Design

Not Significant Now—But Later?

Communicating the Findings


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