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JNCI Journal of the National Cancer Institute 2006 98(5):362-363; doi:10.1093/jnci/djj074
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© The Author 2006. Published by Oxford University Press.

CORRESPONDENCE

Re: Clinical and Biological Features Associated With Epidermal Growth Factor Receptor Gene Mutations in Lung Cancers

Jose R. Pardinas, Li Xiao, Jia Zhang, Kai Li

Affiliations of authors: SNP Institute, Hengyang, China (JRP, LX, KL); Egea Biosciences, LLC., San Diego, CA (JRP); GNF Institute, San Diego, CA (JZ); City of Hope National Medical Center, Duarte, CA (KL)

Correspondence to: Kai Li, MD, PhD, City of Hope National Medical Center, 1500 E. Duarte Rd., Duarte, CA 91010 (e-mail: kli@coh.org).

The first 10% of the full text of this article appears below.

Shigematsu et al. (1) recently described 28 unique epidermal growth factor receptor (EGFR) gene mutations in 617 lung cancer patients and further confirmed the previously described clinical characteristics associated with these somatic mutations. We believe that the authors did not properly annotate two of these mutations (D8 and {Delta}9). For example, they described D8 as a duplication with a nucleotide substitution; we suggest that is more likely to be a simple duplication (Fig. 1, A). In general, it . . . [Full Text of this Article]


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Response to this Correspondence

RESPONSE: Re: Clinical and Biological Features Associated With Epidermal Growth Factor Receptor Gene Mutations in Lung Cancers
Hisayuki Shigematsu, John D. Minna, and Adi F. Gazdar
J Natl Cancer Inst 2006 98: 363-364. [Extract] [Full Text] [PDF]