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JNCI Journal of the National Cancer Institute 2006 98(5):292-293; doi:10.1093/jnci/djj098
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© The Author 2006. Published by Oxford University Press.

EDITORIAL

Etiology and Prevention of Cervical Adenocarcinomas

Allan Hildesheim, Amy Berrington de González

Affiliations of authors: Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD (AH); Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD (ABdG)

Correspondence to: Allan Hildesheim, PhD, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd., Rm. 7062, MSC 7234, Rockville, MD 20852 (e-mail: hildesha@mail.nih.gov).

The first 10% of the full text of this article appears below.

Adenocarcinomas of the uterine cervix (ACs) constitute a relatively rare histologic form of cervical cancer. However, while rates of the more common squamous cell carcinomas of the cervix (SCC) have shown consistent declines in incidence over time in countries where effective cytological screening programs exist, rates of AC have increased over the same period (1–3). This has led to an increase in the proportion of cervical cancers attributable to AC in many countries. In the United States, ACs now make up more than 20% of all cervical cancer cases diagnosed each year (4).

The underlying reasons for the increases observed for AC are not well understood. They are likely due to a complex interplay between temporal changes in exposures . . . [Full Text of this Article]

Etiology

Prevention


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