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Very Early Detection? British Group Gauges Public Interest in Embryo Testing for Cancer
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Last fall, the Human Fertilization and Embryology Authority (HFEA), which regulates British fertility treatment and embryo research, posed a tough question to the public: Should embryo testing for cancer susceptibility genes be made widely available in the United Kingdom?
Preimplantation genetic diagnosis (PGD) can be used in in vitro fertilization to test embryos for conditions such as cystic fibrosis, Huntington disease, and hemophilia. But unlike these diseases, cancer susceptibility conditions have a lower penetrance (that is, not everyone with the faulty gene will develop the cancer); the occurrence of disease may have a later age of onset; and there is the possibility of
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A.L. Bredenoord, G. Pennings, H.J. Smeets, and G. de Wert Dealing with uncertainties: ethics of prenatal diagnosis and preimplantation genetic diagnosis to prevent mitochondrial disorders Hum. Reprod. Update, January 1, 2008; 14(1): 83 - 94. [Abstract] [Full Text] [PDF] |
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