© The Author 2006. Published by Oxford University Press.
EDITORIAL |
Childhood CancerTreatment at a Cost
Affiliation of author: Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.
Correspondence to: Elaine Ron, PhD, Radiation Epidemiology Branch, National Cancer Institute, National Institutes of Health, MS7238, 6120 Executive Blvd., Rm. 7054, Bethesda, MD 20892-7238 (e-mail: eron@mail.nih.gov).
| The first 10% of the full text of this article appears below. |
Over the last 30 years, more effective treatments, as well as enhanced methods for early diagnosis of cancer have resulted in major improvements in survival for childhood malignancies. The relative 5-year survival rate has risen from 56% for children diagnosed between 1974 and 1976 to 79% for those diagnosed in the period 19952001 (1), and the current 10-year survival rate is approximately 75% (2). This increased survival means that the majority of children with cancer can look forward to a long life; however, they may experience multiple late health problems. One of the most alarming long-term consequences of childhood cancer is the occurrence of a second primary malignancy. Although the etiology