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© Oxford University Press 2006.
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Momentum Building for Human Epigenome Project
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Epigenetics does not get the recognition it deserves, say its proponents. "Our struggle in this field has been to convince the community that epigenetics really has a major role in human disease," said Peter Jones, D.Sc., director of the Norris Comprehensive Cancer Center at the University of Southern California in Los Angeles. Jones and 39 other scientists are now trying to convince funding agencies that epigenetics warrants a "Human Epigenome Project." This long-term effort will require substantial but as yet unspecified funds in an era of budget austerity for the National Institutes of Health.
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There is a strong case for such a project. Epigenetics is the study of heritable changes in gene expression that occur without changes in DNA sequencea vast and largely unexplored biological domain. Rudolph Jaenisch, Ph.D., of MIT's Whitehead Institute, has defined epigenetics as "the mechanism to transmit gene expression states from one cell
Charting a Course
Joining the Epigenomics Boom
How Important in Cancer?
Beyond Cancer
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