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Gene Expression Profiling for Neuroblastoma, Breast Cancer
The clinical behavior of metastatic neuroblastomas with a nonamplified MYCN gene generally correlates with the patient's age at diagnosis. However, age at diagnosis is not always associated with patient survival. Asgharzadeh et al. (p. 1193) developed a prognostic classifier of disease progression for children diagnosed with metastatic neuroblastomas lacking MYCN gene amplification based on the expression of 55 genes. The classifier identified patients with low and high progression-free survival rates among those older than 12 months at diagnosis with high-risk disease and those older than 18 months at diagnosis. The authors
Breast Cancer Risk Models Including Breast Density
Use of Lay Health Advisors in Mammography Intervention
Cyclin D1 Overexpression in Breast Cancer and Bortezomib
Radiation-Induced Pneumonitis and CD95