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Circadian Rhythms Play Role in Cancer Research
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Over the years, studies have established that circadian clocks, the internal timekeepers that run many biological processes on a near 24-hour schedule, are associated in some way with tumor growth. What's not known is precisely how the relationship works. But now researchers are uncovering some of the clock's key cancer-related components and beginning to envision a time when manipulating or taking advantage of these internal mechanisms could play a role in treating or even preventing cancer.
"We are just learning which components of the circadian timing system are essential in [tumor development and progression]", says Francis Lévi, M.D., Ph.D., of the Institut National de la Santé et de la Recherche Medicale in Villejuif, France.
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We have "a long way to go to identify specific pathways that are controlled by the circadian clock," says Marina Antoch, Ph.D., of the Lerner Research Institute in Cleveland, "but
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