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Survival and Postmastectomy Adjuvant Radiation Therapy
To determine whether postmastectomy radiation therapy reduces mortality among women with operable breast cancer, Gebski et al. (p. 26) reanalyzed results from 36 clinical trials, in which giving radiation therapy was the only difference between groups in each trial. They found a 2.9% absolute increase in 5-year survival and a 6.4% absolute increase in 10-year survival associated with radiation therapy, compared with no radiation therapy, among trials that used a biologically equivalent dose (BED) of 4060 Gy in 2 Gy fractions with an appropriate target volume. No statistically significant change
Cholesterol-Lowering Drugs and Colorectal Cancer Incidence
G207 and Temozolomide Combination for Glioma
Autoimmune and Inflammatory Disorders and NHL Risk
Reliability of Self-Reported Family History of Cancer
Carbonated Soft Drinks and Risk of Esophageal Cancer