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JNCI Journal of the National Cancer Institute 2005 97(7):476-478; doi:10.1093/jnci/97.7.476
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© 2005 Oxford University Press

NEWS

An Integrated Approach: Systems Biology Seeks Order in Complexity

Robert Longtin

The first 150 words of the full text of this article appear below.

Meet biology's next big intellectual challenge. It's called systems biology, and the discipline has begun to piece together the first detailed sketch of how cells process various biochemical signals, essential information that one day could push more molecular-based cancer treatments closer to reality.

In the last 5 years, universities and institutions such as Harvard and the Massachusetts Institute of Technology have created cross-disciplinary departments devoted to systems biology. New facilities such as Seattle's Institute for Systems Biology have formed with the discipline as their sole mission. So impressed is the National Cancer Institute with this initial work and the prospects of its eventual application in people that officials there recently launched the Integrative Cancer Biology Program to study cancer "as a complex biological system."

Although systems biologists have yet to leave their investigative mark on man or even mouse, they have generated a growing body of elegant research in more . . . [Full Text of this Article]

Defining the Discipline

Culture Clash

Diverging Opinions


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