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JNCI Journal of the National Cancer Institute 2005 97(22):1642-1643; doi:10.1093/jnci/dji422
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© 2005 Oxford University Press

NEWS

Researchers Exploring Implications of Minimal Residual Cancer

Gail McBride

The first 10% of the full text of this article appears below.

Klaus Pantel, M.D., Ph.D., director of the Institute of Tumor Biology at the University of Hamburg in Germany, and colleagues started studying minimal residual cancer more than a decade ago when they began seeking an early marker of cancer's systemic spread. Because bone marrow was routinely tested for micrometastases in leukemia and lymphoma patients, Pantel and his colleagues reasoned that the same approach might work for breast cancer.


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Klaus Pantel

 
Late this summer, their pooled analysis of more than 4,500 breast cancer patients, which was published in the August 25 New England Journal of Medicine, concluded that "the presence of micrometastasis in the bone marrow at the time of diagnosis of breast cancer is associated with a poor prognosis."

"The old view . . . [Full Text of this Article]

Tumor Cells in Peripheral Blood

Tumor Cell Dormancy?

Rare Event Technologies


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