© 2005 Oxford University Press
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Press Release
Study Estimates Melanoma Risk in Gene Mutation Carriers
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
| The first 10% of the full text of this article appears below. |
People who carry a mutation in the melanoma susceptibility gene CDKN2A have a much lower risk of melanoma than has been suggested by previous estimates, although this risk is higher than that in the general population. In addition, most familial clusters of melanoma occur in families without identifiable mutations in