© 2005 Oxford University Press
IN THIS ISSUE |
In This Issue
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Locoregional Radiation Therapy in High-Risk Breast Cancer
In the British Columbia randomized radiation therapy trial, premenopausal
patients with lymph node-positive breast cancer treated by mastectomy and
adjuvant chemotherapy were randomly assigned to no additional treatment or to
receive locoregional radiation therapy. After 20 years of follow-up for this
trial, Ragaz et al. (p.
116) report that radiation therapy and chemotherapy, compared with
chemotherapy alone, was associated with a statistically significant
improvement in all end points analyzed, including isolated locoregional
recurrence, systemic relapse-free survival, disease-free survival, event-free
survival, breast cancer death-free survival, and overall survival. In
addition, long-term toxic effects, including
DNA Repair and Breast Cancer Risk
Role of Human Cripto-1 in Tumor Angiogenesis
Increase in Esophageal Cancer Incidence
Designing SELECT
Epigenetic Changes in Prostate Cancer