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JNCI Journal of the National Cancer Institute 2005 97(2):152-153; doi:10.1093/jnci/dji029
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© 2005 Oxford University Press

CORRESPONDENCE

Re: Polymorphisms Associated With Circulating Sex Hormone Levels in Postmenopausal Women

Francisco De Castro, Francisco J. Moron, Luis Montoro, Jose J. Galan, Luis M. Real, Agustin Ruiz

Affiliations of authors: Unidad de Reproducción Humana Asistida, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, Spain (FC, LM); Departamento de Genómica Estructural. Neocodex, Sevilla, Spain (FJM, JJG, LMR, AR)

Correspondence to: Agustín Ruiz, MD, PhD, Departamento de Genómica Estructural. Neocodex. Edificio Acrópolis Módulos 110-111, c/Averroes no. 8, 41020-Sevilla, Spain (e-mail: aruiz@neocodex.es)

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The Journal recently published a study analyzing the role of sequence variation of genes involved in steroid hormone metabolism in the serum sex hormone levels of postmenopausal women (1). This study concluded that CYP19 and SBGH polymorphisms contribute to the variability in circulating sex hormones in postmenopausal women, although CYP19 or SHBG polymorphisms are only marginally related to breast cancer susceptibility. However, after comparing results from a study we recently published (2. . . [Full Text of this Article]


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Response to this Correspondence

RESPONSE: Re: Polymorphisms Associated With Circulating Sex Hormone Levels in Postmenopausal Women
Alison M. Dunning, Mitch Dowsett, Catherine S. Healey, Robert N. Luben, Elizabeth Folkerd, Paul D. P. Pharoah, Douglas F. Easton, N. E. Day Bruce, and A. J. Ponder
J Natl Cancer Inst 2005 97: 153-154. [Extract] [Full Text] [PDF]



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