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© 2005 Oxford University Press
CORRESPONDENCE |
Re: Medroxyprogesterone Acetate and Metastases: Of Mice and (Wo)Men
Correspondence to: Ann F. Chambers, PhD, London Regional Cancer Program, 790 Commissioners Road East, London, Ontario N6A 4L6, Canada (e-mail: ann.chambers@Lrcc.on.ca).
| The first 10% of the full text of this article appears below. |
I read with interest the article by Palmieri et al. (1), which demonstrated a novel use for the compound medroxyprogesterone acetate. This compound led to reduced metastatic outgrowth of breast cancer cells, apparently via induction of expression of the metastasis suppressor gene Nm23-H1. Because metastases are responsible for
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J Natl Cancer Inst 2005 97: 1225-1226.