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JNCI Journal of the National Cancer Institute 2005 97(15):1110-1112; doi:10.1093/jnci/dji259
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© 2005 Oxford University Press

NEWS

The Big Fat Question: What Is the Role of Excess Weight in Cancer Risk, Mortality?

Renee Twombly

The first 150 words of the full text of this article appear below.

In 1981, British researchers Richard Doll and Richard Peto took on the task of estimating the percentage of cancer deaths in the United States that could be avoided by changing one's lifestyle. In a 119-page article in the Journal of the National Cancer Institute that has since been cited thousands of times, they estimated that tobacco use and poor diet each accounted for about one-third of cancer deaths in the United States. When combined with alcohol consumption, certain infectious conditions, and environmental and occupational carcinogens, Doll and Peto estimated that about 75%–80% of cancer deaths could, in principle, be prevented.

Whereas Doll and Peto linked their conclusions about smoking to a large body of existing evidence, they had much less information on which to base their estimates about diet and nutrition, other than epidemiologic comparisons across countries or studies of immigrants who moved from one country to another. Still, Doll . . . [Full Text of this Article]

Zeroing In on Obesity

Cancer Deaths From Body Fat

No Need for Precise Numbers


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