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JNCI Journal of the National Cancer Institute 2005 97(12):865; doi:10.1093/jnci/97.12.865-a
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© 2005 Oxford University Press

MEMO TO THE MEDIA

Press Release

Phase I Study Examines Biomarkers for Response to Erlotinib in Glioma

Sarah L. Zielinski

jncimedia@oupjournals.org
301-841-1287
Journal of the National Cancer Institute

The first 10% of the full text of this article appears below.

Researchers have found two biomarkers that, in patients with a malignant type of brain tumor called glioblastoma multiforme, were associated with response to the cancer drug erlotinib (Tarceva). Patients with tumors that expressed high levels of epidermal growth factor receptor (EGFR) and low levels of phosphorylated PKB/Akt, an enzyme, responded better to erlotinib than patients with low levels of EGFR expression . . . [Full Text of this Article]


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