© 2004 by Oxford University Press
© 2004 Oxford University Press
Press Release
Small Gene Changes in Some Leukemia Patients May Explain Varying Responses to Chemotherapy
jncimedia@oupjournals.org
301-841-1287
Journal of the National Cancer Institute
| The first 10% of the full text of this article appears below. |
A new study provides evidence that may explain why some patients with chronic lymphocytic leukemia (CLL) are resistant to chemotherapy and have a shorter survival time and may identify a potential new target for treating the disease. Patients who had an insertion in the promoter region of a gene that regulates apoptosis, or programmed cell death, were more likely to have a poor