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JNCI Journal of the National Cancer Institute 2004 96(4):256-257; doi:10.1093/jnci/96.4.256
© 2004 by Oxford University Press
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© 2004 Oxford University Press

NEWS

Connecting Viruses to Cancer: How Research Moves From Association to Causation

Vicki Brower

The first 10% of the full text of this article appears below.

In the past two decades, the study of viruses has contributed greatly to the understanding of cancer biology. But determining that a virus is a cause or a co-factor in cancer is another story, and it is slow, difficult work.

"As tools of discovery, viruses have turned out to be a Rosetta Stone for unlocking the mysteries of cell growth control," said Janet Butel, Ph.D., professor of virology and chairman of the department of molecular virology and microbiology at the Baylor School of Medicine in Houston. Although about 15% of all human tumors worldwide are caused by viruses, there are only five viruses that have been incontrovertibly established as causing cancer, with numerous others under investigation. Key to proving causation is . . . [Full Text of this Article]


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