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JNCI Journal of the National Cancer Institute 2004 96(4):250-251; doi:10.1093/jnci/djh063
© 2004 by Oxford University Press
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© 2004 Oxford University Press

EDITORIALS

Have We Resolved How To Triage Equivocal Cervical Cytology?

Diane Solomon, Mark Schiffman

Affiliations of authors: Breast and Gynecologic Cancer Research Group, Division of Cancer Prevention (DS), and Division of Cancer Epidemiology and Genetics (MS), National Cancer Institute, National Institutes of Health, Rockville, MD

Correspondence to: Diane Solomon, MD, Breast and Gynecologic Cancer Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, 6130 Executive Blvd., Rm. 2130, Rockville, MD 20852 (e-mail: ds87v@nih.gov)

The first 10% of the full text of this article appears below.

Virtually all cases of cervical cancer are caused by one of the 15 or more oncogenic types of human papillomavirus (HPV) infection. With the development and refinement of assays to detect HPV DNA, the question becomes how best to integrate HPV testing into cervical cancer screening, which for more than half a century has relied almost exclusively on the Papanicolaou cervical cytology test. One approach has been to consider HPV testing as a second triage test for the relatively large number of women with borderline, equivocal cytology findings of atypical squamous cells of undetermined significance (ASCUS).

ASCUS encompasses both reactive changes that mimic, but are unrelated to, HPV and . . . [Full Text of this Article]


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Correspondence about this Article

Re: Have We Resolved How To Triage Equivocal Cervical Cytology?
Marc Arbyn, Joakim Dillner, Marc Van Ranst, Frank Buntinx, Pierre Martin-Hirsch, and Evangelos Paraskevaidis
J Natl Cancer Inst 2004 96: 1401-1402. [Extract] [Full Text] [PDF]

RESPONSE: Re: Have We Resolved How To Triage Equivocal Cervical Cytology?
Diane Solomon and Mark Schiffman
J Natl Cancer Inst 2004 96: 1402. [Extract] [Full Text] [PDF]



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