© 2004 by Oxford University Press
© 2004 Oxford University Press
CORRESPONDENCE |
Re: Akt Phosphorylation and Gefitinib Efficacy in Patients With Advanced NonSmall-Cell Lung Cancer
Affiliation of authors: Cancer Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD
Correspondence to: Phillip A. Dennis, MD, PhD, Cancer Therapeutics Branch, National Cancer Institute, National Institutes of Health, 8901 Wisconsin Ave., Bldg. 8, Rm. 5101, Bethesda, MD 20889 (e-mail: dennisp@mail.nih.gov)
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In a recent article in the Journal, Cappuzzo et al. (1) presented data that Akt activation, as assessed by the phosphorylation status of S473 (pAkt), was associated with sensitivity to gefitinib in patients with nonsmall-cell lung cancer (NSCLC). Patients whose
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J Natl Cancer Inst 2004 96: 1795-1796.