© 2004 by Oxford University Press
© 2004 Oxford University Press
CORRESPONDENCE |
RESPONSE: Re: Assessing the Probability That a Positive Report is False: An Approach for Molecular Epidemiology Studies
Affiliations of authors: Biostatistics Branch (SW, HAK), Core Genotype Facility (SC), Hormonal and Reproductive Epidemiology Branch (MGC), and Occupational and Environmental Epidemiology Branch (NR), Division of Cancer Epidemiology and Genetics, and Pediatric Oncology Branch, Center for Cancer Research (SC), National Cancer Institute, National Institutes of Health, Bethesda, MD; George Washington University, Biostatistics Center, Rockville (LE)
Correspondence to: Sholom Wacholder, PhD, Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-7244 (e-mail: wacholder@nih.gov)
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Dr. Dubben notes that a study with higher statistical power will have a lower false-positive report probability (FPRP) than a study with lower statistical power, as seen in equation 1 and in figures 1 and 2 of our original paper (1). He is puzzled, however, by figure 5 (1), which shows FPRP increasing with increasing statistical power.
Our paper's figure 5 (1
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J Natl Cancer Inst 2004 96: 1722.