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JNCI Journal of the National Cancer Institute 2004 96(17):1272-1273; doi:10.1093/jnci/96.17.1272
© 2004 by Oxford University Press
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© 2004 Oxford University Press

NEWS

Recent Work Adds Support to Theory That Cells May Have Metastatic Origin

Karyn Hede

The first 10% of the full text of this article appears below.

For years, medical science has looked for clues to what makes cancer cells different from normal cells by studying the telltale changes in the DNA code. But the answer may lie in the very structure of the DNA polymer itself, according to Donald Malins, Ph.D, D.Sc., and his colleagues at Pacific Northwest Research Institute in Seattle.


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  		Dr. Donald Malins

 

In back-to-back studies, Malins' team reported that they can detect changes in the structure of DNA that can predict a cancer phenotype in cells before tumors form and furthermore can distinguish metastatic from nonmetastatic cells.

Using Fourier transform-infrared spectroscopy . . . [Full Text of this Article]


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