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JNCI Journal of the National Cancer Institute 2004 96(13):987-989; doi:10.1093/jnci/96.13.987
© 2004 by Oxford University Press
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© 2004 Oxford University Press

NEWS

Chew on This: Mutation May Be Responsible for Tooth Loss, Colon Cancer

Robert Longtin

The first 10% of the full text of this article appears below.

A decade ago, scientists sometimes explained the ABCs of genetics with the simple rule that each gene has one function. Today, this nice, neat and, as some would say, naive concept appears to have fallen largely out of favor. In its place, researchers have fashioned the concept in which a gene typically has multiple functions and/or physiologic effects, sometimes in seemingly unrelated parts of the body.

Just how seemingly unrelated can these manifestations be? Recently, a team of Finnish scientists reported discovering a large family that is predisposed to both colon cancer and a rare congenital dental malformation. They say the cause . . . [Full Text of this Article]

All in the Family

Molecular Logic


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