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JNCI Journal of the National Cancer Institute 2004 96(12):968-969; doi:10.1093/jnci/djh179
© 2004 by Oxford University Press
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© 2004 Oxford University Press

CORRESPONDENCE

RESPONSE: Re: Human Papillomavirus DNA and p53 Polymorphisms in Squamous Cell Carcinomas From Fanconi Anemia Patients

David I. Kutler, Volkert B. Wreesmann, Bhuvanesh Singh

Affiliation of authors: Laboratory of Epithelial Cancer Biology, Memorial Sloan-Kettering Cancer Center, New York, NY

Correspondence to: Bhuvanesh Singh, MD, Laboratory of Epithelial Cancer Biology, Memorial Sloan-Kettering Cancer Center, 1275 York Ave., New York, NY 10021 (e-mail: singhb@mskcc.org)

The first 10% of the full text of this article appears below.

We reported a high prevalence of human papillomavirus (HPV) DNA and the absence of p53 mutations among 24 squamous cell carcinomas (SCCs) from 25 Fanconi anemia patients (1). By contrast, van Zeeburg et al. describe an unpublished series of five cases of head and neck squamous cell carcinoma (HNSCC) from Fanconi anemia patients in which they identified mutations in p53 in four cases and the absence of detectable HPV DNA in all cases.

Several factors may explain . . . [Full Text of this Article]


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Related Correspondence

Re: Human Papillomavirus DNA and p53 Polymorphisms in Squamous Cell Carcinomas From Fanconi Anemia Patients
Hester J. T. van Zeeburg, Peter J. F. Snijders, Hans Joenje, and Ruud H. Brakenhoff
J Natl Cancer Inst 2004 96: 968. [Extract] [Full Text] [PDF]



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