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JNCI Journal of the National Cancer Institute 2004 96(11):816-818; doi:10.1093/jnci/96.11.816
© 2004 by Oxford University Press
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© 2004 Oxford University Press

NEWS

Debate Rages Over Proteomic Patterns

Ken Garber

The first 150 words of the full text of this article appear below.

One controversy aired in numerous sessions and hallways at this year’s American Association for Cancer Research annual meeting was the future of proteomic patterns in cancer diagnosis. Can protein "signatures," generated by mass spectrometers, accurately and reliably distinguish cancer from noncancer?

This idea has generated a tremendous amount of excitement among researchers—as well as wide national publicity—because it could, in theory, lead to a rapid, universal blood test for cancer. But critics have recently begun to raise their voices against the pattern concept. "The validity of the method is questionable at the moment," said Eleftherios Diamandis, M.D., Ph.D., a cancer biomarkers expert at the University of Toronto.


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  		Dr. Eleftherios Diamandis

 
Diamandis, who has penned several critiques of the protein pattern approach (for example, see JNCI, Vol. 96, No. 5, p. 353), was speaking at a packed AACR forum. Emanuel "Chip" Petricoin, Ph.D., the Food and Drug Administration scientist . . . [Full Text of this Article]

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