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JNCI Journal of the National Cancer Institute 2004 96(10):732-734; doi:10.1093/jnci/96.10.732
© 2004 by Oxford University Press
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© 2004 Oxford University Press

NEWS

Metabolomics Takes Its Place as Latest Up-and-Coming "Omic" Science

Charlie Schmidt

The first 150 words of the full text of this article appear below.

Since the emergence of genomics—which refers to global studies of gene expression—several other "omic" techniques have come to the fore, each promising great medical advances.

Among these latter-day omics are proteomics, global studies of protein expression, and transcriptomics, which are genome-wide studies of mRNA. But despite high expectations, an omic payoff in medicine has been slow in coming. Omic sciences are bogged down by technical limitations, database challenges, and exorbitant costs. Indeed, scientists concede that progress in these promising fields is likely to be slower and more tedious than was once expected.

Today, yet another omic science has begun to emerge: metabolomics, the study of global metabolite profiles in cells, tissues, and organisms. These profiles are typically generated with high-throughput nuclear magnetic resonance (NMR) spectroscopy and mass spectroscopy (MS). The extent to which the field is actually "new" is up for debate: Scientists have been using these analytical techniques to . . . [Full Text of this Article]

An Emphasis on Biofluids

Tumor Analysis

Database Needs


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