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JNCI Journal of the National Cancer Institute 2003 95(9):638-639; doi:10.1093/jnci/95.9.638
© 2003 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 95, No. 9, 638-639, May 7, 2003
© 2003 Oxford University Press

NEWS

Recent Studies Attempt to Clarify Relationship Between Oral Cancer and Human Papillomavirus

Jeanne Erdmann

The first 10% of the full text of this article appears below.

Although tobacco and alcohol are responsible for most oral cancers, physicians are reporting an increase in the disease in patients with little or no history of smoking or drinking. Some of these cancers contain the human papillomavirus (HPV), most especially HPV16, a sexually transmitted member of the papillomavirus family linked to about half of all cases of cervical cancer.


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  		When human papillomavirus attacks the tonsil area, the cells take on a distinctive "basaloid" look. The unique shape and appearance are unlike that of oral cancer caused by tobacco or alcohol. (Source: J Natl Cancer Inst 2000;92:709–20[Abstract/Free Full Text])

 
For many years, the medical community was divided between those who were skeptical that HPV could be a risk factor for oral cancer and those who remained convinced enough to field large research projects. More than 20 years . . . [Full Text of this Article]


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