Skip Navigation

JNCI Journal of the National Cancer Institute 2003 95(8):571-573; doi:10.1093/jnci/95.8.571
© 2003 by Oxford University Press
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Mandel, J. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mandel, J. S.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Journal of the National Cancer Institute, Vol. 95, No. 8, 571-573, April 16, 2003
© 2003 Oxford University Press

EDITORIAL

Sigmoidoscopy Screening Probably Works, but How Well Is Still Unknown

Jack S. Mandel

Correspondence to: Jack S. Mandel, Ph.D., M.P.H., Department of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Rd. NE, Atlanta, GA 30322 (e-mail: jsmande@sph.emory.edu).

The first 10% of the full text of this article appears below.

The most persuasive scientific evidence for the benefit of a cancer screening test comes from a randomized controlled clinical trial (RCT) where the endpoint is a reduction in mortality from (or incidence of) the disease of interest. There have been three RCTs of a fecal occult blood test (Hemoccult; Beckman Coulter, Palo Alto, CA) for early detection of colorectal cancer involving more than 250 000 people that have shown consistent results (1–5). Unfortunately, for the other colorectal cancer screening methods (i.e., sigmoidoscopy, colonoscopy, virtual colonoscopy, barium enema, and other fecal occult blood tests), there is no adequately completed trial that provides a valid estimate of the effect of screening. RCTs are currently underway to evaluate sigmoidoscopy (6,7), and a pilot study has been implemented to examine the benefits . . . [Full Text of this Article]


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?