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JNCI Journal of the National Cancer Institute 2003 95(22):1655; doi:10.1093/jnci/95.22.1655
© 2003 by Oxford University Press
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© 2003 Oxford University Press

NEWS

In Brief

Linda Wang

The first 10% of the full text of this article appears below.

Researchers Identify Cause of Gene Therapy-Induced Leukemia

Researchers have determined why two children with X-linked severe combined immunodeficiency (SCID-X1) developed a leukemia-like syndrome nearly 3 years after being treated with gene therapy. The children were 2 of 10 patients in a clinical trial in France.

A known risk of gene therapy is insertional mutagenesis, or the insertion of a retroviral vector, which could activate a proto-oncogene or inactivate a tumor . . . [Full Text of this Article]

Study Backs 3-Year Interval for Cervical Cancer Screening

Cholesterol-Lowering Drugs Associated With Lower Risk of Breast Cancer

Task Forces Issue Recommendations for Preventing Skin Cancer


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