© 2003 by Oxford University Press
© 2003 Oxford University Press
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Re: Zinc Supplement Use and Risk of Prostate Cancer
Affiliations of authors: C. A. Krone, Applied Research Institute, Palmerston North, New Zealand; L. C. Harms, Applied Research Institute, Evanston, IL.
Correspondence to: Cheryl A. Krone, PhD, Applied Research Institute, P.O. Box 1969, Palmerston North, New Zealand (e-mail: cakrone@u.washington.edu).
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Although the etiology of prostate cancer is still virtually unknown, some epidemiologic, experimental, and dietary supplement studies have provided evidence of a protective role for zinc in the development and progression of prostate malignancy. However, results of other studies have suggested that high intraprostatic zinc levels may increase prostate cancer risk. The recent study in the Journal by Leitzmann et al. (1
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J Natl Cancer Inst 2003 95: 1556-1557.