© 2003 by Oxford University Press
© 2003 Oxford University Press
CORRESPONDENCE |
Re: Quantitative Association Between HER-2/neu and Steroid Hormone Receptors in Hormone Receptor-Positive Primary Breast Cancer
Affiliations of authors: F. Spyratos (Laboratoire dOncobiologie), C. Bouchet, M. Ferrero-Poüs (Département de Biologie), M. Tubiana-Hulin (Département de Médecine), K. Hacène (Département de Statistiques Médicales), Centre René Huguenin de Lutte Contre le Cancer, Saint Cloud, France.
Correspondence to: Dr. Frédérique Spyratos, Centre René Huguenin de Lutte Contre le Cancer, Laboratoire dOncobiologie, 35 rue Dailly, 92210 Saint Cloud, France (e-mail: f.spyratos@stcloud-huguenin.org).
| The first 10% of the full text of this article appears below. |
Recent clinical data (1) suggest that c-erbB-2 overexpression/amplification might be associated with tamoxifen resistance in patients with estrogen receptor (ER)-positive tumors. This association is controversial, however, and the question of the efficacy of hormone therapy in these patients is still a matter of debate. In a recent issue of the Journal, Konecny et al.