© 2003 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 95, No. 12, 845,
June 18, 2003
© 2003 Oxford University Press
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First Proteasome Inhibitor Approved for Multiple Myeloma
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Velcade (bortezomib), the first in a new class of investigational drugs known as proteasome inhibitors, was approved for use in multiple myeloma in record-making timeonly 4 months after it had been submitted to the U.S. Food and Drug Administration.
"The drug shows a significant effect on patients with multiple myeloma that have not responded to other treatmentsa response that is likely to result in
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