Skip Navigation

JNCI Journal of the National Cancer Institute 2003 95(12):842-843; doi:10.1093/jnci/95.12.842
© 2003 by Oxford University Press
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (16)
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Granath, F.
Right arrow Articles by Törnqvist, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Granath, F.
Right arrow Articles by Törnqvist, M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Journal of the National Cancer Institute, Vol. 95, No. 12, 842-843, June 18, 2003
© 2003 Oxford University Press

EDITORIAL

Who Knows Whether Acrylamide in Food Is Hazardous to Humans?

Fredrik Granath, Margareta Törnqvist

Affiliations of authors: F. Granath, Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, SE-171 76 Stockholm, Sweden; M. Törnqvist, Department of Environmental Chemistry, Stockholm University, SE-106 91 Stockholm.

Correspondence to: Fredrik Granath, Ph.D., Clinical Epidemiology Unit, Department of Medicine, Karolinska Hospital M9:01, SE-171 76 Stockholm, Sweden (e-mail: Fredrik.Granath@mep.ki.se).

The first 10% of the full text of this article appears below.

In this issue of the Journal, Besaratinia and Pfeifer (1) add to the toxicologic evidence that acrylamide has the ability to induce genetic damage in mammalian cells. Acrylamide or probably glycidamide, its genotoxic metabolite, has a relatively low mutagenic potency and is likely to have a relatively small impact on the overall cancer risk of an individual. However, because rather high concentrations of acrylamide are found in frequently consumed foods, the total acrylamide burden to a population is large. If one is willing to assume that a low-dose linear relationship between acrylamide exposure and carcinogenicity exists, then the contribution of acrylamide to the total cancer incidence in a population may be important. The expectedly low carcinogenicity will, however, create difficulties in applying epidemiologic studies, and the uncertainties associated . . . [Full Text of this Article]


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 JNCI J Natl Cancer InstHome page
L. A. Mucci and H.-O. Adami
The Plight of the Potato: Is Dietary Acrylamide a Risk Factor for Human Cancer?
J Natl Cancer Inst, May 6, 2009; 101(9): 618 - 621.
[Full Text] [PDF]