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JNCI Journal of the National Cancer Institute 2002 94(7):530; doi:10.1093/jnci/94.7.530
© 2002 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 94, No. 7, 530, April 3, 2002
© 2002 Oxford University Press

CORRESPONDENCE

Re: Night Shift Work, Light at Night, and Risk of Breast Cancer

David Spiegel, Sandra Sephton

Affiliations of authors: D. Spiegel, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA; S. Sephton, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, KY.

Correspondence to: David Spiegel, M.D., Dept. of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305–5718 (e-mail: dspiegel@stanford.edu; web address:pstlab.stanford.edu ).

Two studies recently published in the Journal showed that disruption of diurnal sleep–wakefulness rhythms, especially through nighttime shift work, was associated with higher subsequent breast cancer incidence (1,2). Both of the articles and the accompanying editorial cited melatonin suppression as a likely mediator via reduced suppression of ovarian estrogen . . . [Full Text of this Article]

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