© 2002 by Oxford University Press
Journal of the National Cancer Institute, Vol. 94, No. 6, 461-462,
March 20, 2002
© 2002 Oxford University Press
CORRESPONDENCE |
Re: Familial Multiple Myeloma: a Family Study and Review of the Literature
Affiliations of authors: Department of Genetic Oncology/Institut National de la Santé et de la Recherche Médicale (INSERM), Equipe Propre INSERM (EPI) 9939, Paoli-Calmettes Institute, Marseille, France, and Université de la Méditerranée, Marseille; Department of Medicine, Paoli-Calmettes Institute, Marseille; Department of Genetic Oncology/INSERM, EPI 9939, Paoli-Calmettes Institute, Marseille; Department of Medical Genetics, Hôpital de la Timone, and Université de la Méditerranée, Marseille.
Correspondence to: Professor Hagay Sobol, M.D., Ph.D., Department of Genetic Oncology/Institut National de la Santé et de la Recherche Médicale, EPI 9939, Paoli-Calmettes Institute, 13009 Marseille, France (e-mail: sobol@marseille.inserm.fr).
Multiple myeloma (MM) is one of the hematologic malignancies with the poorest outlook. Although very little is known about the causes and the molecular defects underlying MM development, the identification of familial clusters of MM has suggested possible involvement of genetic factors. In this respect, Lynch et al. (1) have reported on a family in which three siblings have MM. Although such families are rare, they represent a precious resource for identifying the genes that
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H. T. Lynch, P. Watson, S. Tarantolo, P. H. Wiernik, B. Quinn-Laquer, K. Isgur Bergsagel, L. Huiart, O.I. Olopade, H. Sobol, W. Sanger, et al. Phenotypic Heterogeneity in Multiple Myeloma Families J. Clin. Oncol., February 1, 2005; 23(4): 685 - 693. [Abstract] [Full Text] [PDF] |
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