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JNCI Journal of the National Cancer Institute 2002 94(4):244-245; doi:10.1093/jnci/94.4.244
© 2002 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 94, No. 4, 244-245, February 20, 2002
© 2002 Oxford University Press

NEWS

Mutation Analysis Suggests Role for Ribonuclease L Gene in Prostate Cancer

F. B. Dunn

After a decade of scrutinizing family trees and DNA, a multi-institutional team has discovered a genetic mutation linked to prostate cancer. Preliminary evidence marks the mutations in the once obscure RNASEL gene on chromosome 1 as responsible for just a tiny percentage of all cases of prostate cancer. However, some tantalizing data suggest that these cases may be among the most aggressive.

"The individuals who carry the mutations seem to present with cancer that leads to poor outcomes," said John Carpten, Ph.D., of the National Human Genome Research . . . [Full Text of this Article]

Two Families

Three Streams


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