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JNCI Journal of the National Cancer Institute 2002 94(3):229-230; doi:10.1093/jnci/94.3.229-a
© 2002 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 94, No. 3, 229-230, February 6, 2002
© 2002 Oxford University Press

CORRESPONDENCE

Re: Debate on the Link Between SV40 and Human Cancer Continues

Michele Carbone, Harvey I. Pass

Affiliations of authors: M. Carbone, Cardinal Bernardin Cancer Center, Loyola University Medical School Chicago, Maywood IL; H. I. Pass, Karmanos Cancer Institute, Wayne State University, Detroit, MI.

Correspondence to: Michele Carbone, M.D., Ph.D., Cardinal Bernardin Cancer Center Room 205, Loyola University Medical School Chicago, 2160 S. First Ave., Rm. 205, Maywood, IL 60153 (e-mail: mcarbon@orion.it.luc.edu).

Overall, Nancy Nelson's news article about simian virus 40 (SV40) and human tumors (1) was well balanced. We would like to make some additional comments. (More information can be found in the February 2001 issue of Seminars in Cancer Biology.)

First, the statement in the sidebar that SV40 causes "abnormalities" in human cells underestimates the extent of damage. Human cells infected by SV40 in vitro develop extensive genetic . . . [Full Text of this Article]

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