© 2002 by Oxford University Press
Journal of the National Cancer Institute, Vol. 94, No. 22, 1722-1723,
November 20, 2002
© 2002 Oxford University Press
CORRESPONDENCE |
Re: The Influence of Menstrual Cycle Phase on Surgical Treatment of Primary Breast Cancer: Have We Made Any Progress Over the Past 13 Years?
R. R. Love, D. L. DeMets, University of Wisconsin, Madison; D. C. Allred, Baylor College of Medicine, Waco, TX.
Correspondence to: Richard R. Love, M.D., M.S., Medical Oncology Section, Department of Medicine, University of Wisconsin School of Medicine, 610 Walnut St., 256 WARF, Madison, WI 53705 (e-mail: rrlove@facstaff.wisc.edu).
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Although we appreciate Dr. Hortobagyis (1) editorial interest in our study (2), and in particular his call for a prospective randomized trial addressing the hypothesis we have proposed, that adjuvant luteal phase surgical oophorectomy is statistically significantly more effective than follicular phase oophorectomy, we believe he has mischaracterized the nature and results of our study.
We reported secondary analyses of data obtained prospectively in a trial designed to investigate the impact of adjuvant oophorectomy and tamoxifen in premenopausal