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JNCI Journal of the National Cancer Institute 2002 94(16):1187-1188; doi:10.1093/jnci/94.16.1187
© 2002 by Oxford University Press
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Journal of the National Cancer Institute, Vol. 94, No. 16, 1187-1188, August 21, 2002
© 2002 Oxford University Press

EDITORIAL

St. John's Wort: More Implications for Cancer Patients

Patrick J. Mansky, Stephen E. Straus

Affiliation of authors: P. J. Mansky, S. E. Straus, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, MD.

Correspondence to: Stephen E. Straus, M.D., Director, NCCAM/NIH, Bldg. 31, Rm. 2B-11, 31 Center Dr., Bethesda, MD 20892 (e-mail: sstraus@nih.gov).

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St. John's wort (Hypericum perforatum L.) has been used as a medicinal plant in Europe and Asia for centuries. Although it is best known today for its use by patients with mild to moderately severe depression, St. John's wort has also been used orally as a traditional treatment for excitability, neuralgia, fibrositis, sciatica, and anxiety and as a topical preparation for the treatment of wounds (1). Concerns over its use have been raised with the recognition that, whatever its beneficial health effects might be, St. John's wort interacts powerfully with many important drugs, potentially mitigating their effects (1). . . [Full Text of this Article]


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